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Biggest Single-Week Fantasy Performances of 2021

Ja'Marr Chase of the Cincinnati Bengals owned the biggest single-week fantasy performance of 2021, posting 56 fantasy points in his best game of the year. Jonathan Taylor of the Indianapolis Colts came next at 53, with Derrick Henry of the Tennessee Titans and Tyreek Hill of the Kansas City Chiefs tied at 48. Chase led the list with 305 season points in 2021.

The Ten Best Single-Week Fantasy Scores of 2021

Every figure below is taken directly from the recorded 2021 season data, ranked by best single-week fantasy points. The final column is the one this page is about: the highest score each player posted in any one game that year.

| Rank | Player | Team | Games | Points | Points Per Game | Best Week | | 1 | Ja'Marr Chase | Cincinnati Bengals | 17 | 305 | 18 | 56 | | 2 | Jonathan Taylor | Indianapolis Colts | 17 | 373 | 22 | 53 | | 3 | Derrick Henry | Tennessee Titans | 9 | 191 | 21 | 48 | | 4 | Tyreek Hill | Kansas City Chiefs | 17 | 296 | 17 | 48 | | 5 | Leonard Fournette | Tampa Bay Buccaneers | 15 | 256 | 17 | 44 | | 6 | Tee Higgins | Cincinnati Bengals | 16 | 217 | 14 | 43 | | 7 | Austin Ekeler | Los Angeles Chargers | 17 | 340 | 20 | 42 | | 8 | Aaron Jones | Green Bay Packers | 17 | 229 | 13 | 42 | | 9 | Travis Kelce | Kansas City Chiefs | 17 | 263 | 15 | 41 | | 10 | Justin Herbert | Los Angeles Chargers | 17 | 369 | 22 | 41 |

Why Ja'Marr Chase's 56-Point Week Was the Standout Game of 2021

Chase's best week of 56 sits above every other single-game score in this group, and the margin is visible rather than marginal: the next best week anywhere in the table is 53. Chase topped the list with 305 points in 2021, and his 56-point best week was the largest single game among these ten names.

The Bengals placed two receivers in this group, and Chase's 18 points per game led Higgins's 14. A best week of 56 against an average of 18 means his peak game was roughly triple his typical output, the widest such spread at the top of the table.

How the Rest of the Best-Week Column Shook Out

Jonathan Taylor, whose 373 season points were the most recorded by anyone in this ten, posted a best week of 53 and a per-game mark of 22 that only Justin Herbert matched. Derrick Henry matched Tyreek Hill at 48 despite playing 9 games to Hill's 17, and his 21 points per game ranked among the best rates here. Leonard Fournette followed at 44 for the Tampa Bay Buccaneers, with Tee Higgins one behind at 43.

Austin Ekeler and Aaron Jones share 42, though their seasons looked nothing alike: Ekeler totaled 340 points to Jones's 229. Travis Kelce closed the group at 41, and Justin Herbert's 41 is the lowest best week on the board despite his 369 season points, the second-highest total listed. Herbert's case shows the difference between steady week-to-week scoring, which his 22 points per game reflects, and one towering game like Chase's.

What the Best-Week Numbers Say About 2021

The best-week column compresses quickly. From Chase's 56 down to Herbert's 41, the whole range of peak games spans just a handful of scores, and three pairs of players sit tied: 48, 42 and 41. The Kansas City Chiefs and the Los Angeles Chargers each placed two players on the list.

For anyone judging boom games rather than season totals, the order changes. Chase, not Taylor, owns the top spot; Henry produced a 48-point best week while playing only 9 games; and Ekeler sits seventh on peak game alone. Peak scoring and total scoring told two different stories in 2021, and Chase wrote the headline of the year.

Common questions

Who had the biggest single-week fantasy performance in 2021?

Ja'Marr Chase of the Cincinnati Bengals, with 56 fantasy points in his best game of the 2021 season. No other player in the recorded top ten exceeded 53 in a single week.

What was Jonathan Taylor's best fantasy week in 2021?

Taylor's best week of 2021 was 53 fantasy points. He scored 373 fantasy points in 17 games for the Indianapolis Colts, averaging 22 per game.

Did Derrick Henry have a bigger fantasy week than Tyreek Hill in 2021?

No. Both recorded a best week of 48 fantasy points in 2021, an exact tie. Henry did it in 9 games for the Tennessee Titans while Hill played 17 for the Kansas City Chiefs.

Which quarterback had the highest single-week fantasy score in 2021 among the top scorers?

Justin Herbert of the Los Angeles Chargers, with a best week of 41 fantasy points. He finished the season with 369 fantasy points, the second-highest total in the recorded top ten.

How did the Cincinnati Bengals place two players on the 2021 best-week list?

Ja'Marr Chase led the season's peak games at 56 and totaled 305 fantasy points, while teammate Tee Higgins posted a best week of 43 and 217 points across 16 games. They were the only pair of teammates from the same team other than the two Kansas City Chiefs and two Los Angeles Chargers entries.

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Published 2026-09-03. Projections refresh weekly, on Tuesdays at around 09:00 UTC.